Although sonodynamic therapy (SDT) is a promising non-invasive tumor treatment strategy due to its safety, tissue penetration depth and low cost, the hypoxic tumor microenvironment limits its therapeutic effects.Herein, we have designed and developed an oxygen-independent, ROS-amplifying chemo-sonodynamic antitumor therapy based on novel pH/GSH/ROS
The aim of this paper is to develop a functional approach to optimize the engagement effectiveness of the tactical homing missiles and air defense systems by utilizing the differential geometric concepts.In this paper the engagement geometry of the interceptor and the target is developed and expressed in differential geometric terms in order to dem
Introduction: Pain from the head and neck is linked to the trigeminal pathway and three neurons participate: a first-order neuron located in the trigeminal ganglion, a second-order neuron from the subnucleus caudalis of the trigeminal nerve, and a third-order neuron which starts from the medial area of the ventrobasal thalamus complex and ends in t
INTRODUCTION: helminthic infections caused by soil-transmitted helminths (STH) and schistosomes are among the most prevalent afflictions of humans who live in areas of poverty.An operational research was undertaken in 5 villages of Kwale County during a pilot control programme which included both the adults and school going children.Willingness of
We propose an application-oriented nonlinear control approach for centrifugal compressors, tailored to meet requirements of walkkick industrial applications such as variable process demands and adherence to operational constraints, for instance surge avoidance.Our compressor model modifies an approach of Gravdahl and Egeland by including key featur